Synthetic vs Natural Vitamin B12

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This podcast is in response to a question relating to the difference between synthetic and natural vitamin B12.

The synthetic version of vitamin B12 is called cyanocobalamin. The natural version of vitamin B12 is called methylcobalamin.

The main reason why people get synthetic vitamin B12 is that it’s cheaper. In many cases, on the label of synthetic vitamin B12, it will say something like 5000%. But, more is not always better. The reason why it’s 5000% is that it takes so much of it to be absorbed.


Cyanocobalamin (synthetic vitamin B12):

• Is not easily absorbed

• Splits of into cyanide


Methylcobalamin (natural vitamin B12):

• Bonds to protein (needs stomach acid to break it down)

• You also need the intrinsic factor


* I recommend methylcobalamin (natural vitamin B12). Most animal products are also filled with vitamin B12.


You might have a problem absorbing vitamin B12 if you:

• Have low stomach acid

• Have atrophic gastritis (take Zypan)

• Had stomach surgery

• Take metformin

• Are a vegan (you can get B12 from wheatgrass juice powder)


Side effects of a vitamin B12 deficiency:

 • Diarrhea

 • Nausea

 • Upset stomach

 • Rash

 • Headaches

 • Dizziness 

 • Joint pain

 • Fatigue


B12 is involved in:

1. The production of red blood cells

2. Brain function/nerve function

3. The creation of DNA


Dr. Eric Berg DC Bio:

Dr. Berg, 51 years of age is a chiropractor who specializes in weight loss through nutritional & natural methods. His private practice is located in Alexandria, Virginia. His clients include senior officials in the U.S. government & the Justice Department, ambassadors, medical doctors, high-level executives of prominent corporations, scientists, engineers, professors, and other clients from all walks of life. He is the author of The 7 Principles of Fat Burning.

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